Urinary β2-Microglobulin is a Sensitive Indicator for Renal Tubular Injury
نویسندگان
چکیده
domain of the immunoglobulin molecule [3]. β2-microglobulin forms the invariant light chain portion of major histocompatibility complex (MHC) class I molecules [4-6], which can be found on the membrane of all nucleated cells [7]. Thus, cellular membrane turnover is the main source of serum β2-microglobulin [3]. Because of its small size, β2-microgloUrinary β2-Microglobulin is a Sensitive Indicator for Renal Tubular Injury Zeng X1*, Hossain D2, Bostwick DG2, Herrera GA3, Ballester B2 and Zhang PL4
منابع مشابه
Urinary β2-Microglobulin Is a Good Indicator of Proximal Tubule Injury: A Correlative Study with Renal Biopsies
Objective. After filtration through glomeruli, β2-microglobulin is reabsorbed in proximal tubules. Increased urinary β2-microglobulin indicates proximal tubule injury and measurement of β2-microglobulin in urine is useful to determine the source of renal injury. Kidney injury molecule-1 (KIM-1) has been characterized as a selective proximal tubule injury marker. This study was designed to evalu...
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